Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626875 | 0.79 | ALDH1A1 (0.37) | LMNASMN1; SMN2HIF1A | |
| SCHEMBL1444909 | 0.78 | MAPT (0.38) | LMNASMN1; SMN2EDNRBEDNRAGABRP | |
| Hydrochloric Acid SCHEMBL27338358 | 0.77 | MAPT (0.37) | LMNASMN1; SMN2HIF1AEDNRBEDNRA | |
| SCHEMBL28173680 | 0.72 | MAPT (0.31) | — | |
| SCHEMBL17320675 | 0.72 | LMNA (0.46) | LMNASMN1; SMN2HIF1AEDNRBEDNRA | |
| SCHEMBL2934359 | 0.68 | MAPT (0.40) | LMNASMN1; SMN2HIF1AGABRPGABRD | |
| SCHEMBL1450636 | 0.67 | GABRP (0.34) | LMNASMN1; SMN2HIF1AGABRPGABRD | |
| SCHEMBL28846735 | 0.64 | GABRP (0.35) | LMNASMN1; SMN2HIF1AGABRPGABRD | |
| SCHEMBL6778036 | 0.61 | NPSR1 (0.35) | — | |
| SCHEMBL19732864 | 0.61 | MAOA (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402459-A | Method and device for synthesizing 4-hydroxyquinoline-3-formic acid | 贵州中医药大学 | 2021-09-17 | — | — | CN | disclosed |