SCHEMBL10422684

SCHEMBL10422684

Cc1ccc([Se]c2ccc(C)cc2)cc1.[Na]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 3/20 0.43
TSHR P16473 3/20 0.43
GAA P10253 1/20 0.41
CA7 P43166 3/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CA12 O43570 1/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
CHRNA7 P36544 1/20 0.38
LMNA P02545 2/20 0.37
ALOX12 P18054 1/20 0.37
TLR9 Q9NR96 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3891882 0.97 ACHE (0.57) ACHETDP1ALDH1A1TSHRCA7
SCHEMBL5887510 0.85 ACHE (0.53) ACHETDP1ALDH1A1TSHRCA7
Water SCHEMBL29177527 0.73 ACHE (0.53) ACHETDP1ALDH1A1TSHRCA7
P-Xylene SCHEMBL460348 0.73 ACHE (1.00) ACHETDP1ALDH1A1TSHRGAA
P-Xylene SCHEMBL11772917 0.73 ACHE (1.00) ACHETDP1ALDH1A1TSHRGAA
P-Xylene SCHEMBL11770184 0.73 ACHE (1.00) ACHETDP1ALDH1A1TSHRGAA
P-Xylene SCHEMBL771 0.73
SCHEMBL20746498 0.71
P-Xylene SCHEMBL19307687 0.70 ACHE (0.73) ACHETDP1ALDH1A1TSHRGAA
P-Xylene SCHEMBL461064 0.69 ACHE (0.89) ACHETDP1ALDH1A1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4900782-A Stabilized polyelectrolyte precursors of poly(aromatic and heteroaromatic vinylenes) ALLIED-SIGNAL INC. (US) 1990-02-13 US disclosed