Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421319 | 0.84 | CYP4A11 (0.57) | POLBL3MBTL1KMT2A | |
| SCHEMBL8577834 | 0.82 | POLB (0.63) | POLBALDH1A1KMT2A | |
| SCHEMBL10422361 | 0.82 | L3MBTL1 (0.63) | ALDH1A1L3MBTL1 | |
| SCHEMBL23417615 | 0.82 | POLB (0.77) | POLBALDH1A1KMT2A | |
| SCHEMBL30971354 | 0.82 | POLB (0.60) | POLBALDH1A1KMT2A | |
| SCHEMBL10627917 | 0.82 | L3MBTL1 (0.83) | L3MBTL1 | |
| SCHEMBL10893730 | 0.81 | POLB (0.71) | POLBALDH1A1 | |
| SCHEMBL28742538 | 0.81 | POLB (0.86) | POLBKMT2A | |
| SCHEMBL10421956 | 0.81 | L3MBTL1 (0.61) | L3MBTL1 | |
| SCHEMBL27446239 | 0.80 | SMN1; SMN2 (0.81) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933325-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE & CO. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4880829-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE AND COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| US-4847241-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| US-4822775-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0215297-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-25 | — | — | EP | disclosed |