Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924560 | 0.90 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27446239 | 0.85 | SMN1; SMN2 (0.81) | POLBSMN1; SMN2 | |
| SCHEMBL17198866 | 0.84 | POLB (0.55) | POLBSMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28484534 | 0.83 | POLB (0.54) | POLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28850813 | 0.82 | MTNR1A (0.77) | KMT2AMEN1 | |
| SCHEMBL10422980 | 0.82 | POLB (0.74) | POLBKMT2AALDH1A1 | |
| SCHEMBL29991337 | 0.82 | MTNR1A (0.77) | KMT2AMEN1 | |
| SCHEMBL10519203 | 0.82 | POLB (0.57) | POLBSMN1; SMN2KMT2A | |
| SCHEMBL10841849 | 0.81 | MTNR1A (0.62) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL25335984 | 0.81 | CYP2D6 (0.68) | POLBSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719279-A | CHOLINOMIMETICS | BOEHRINGER INGELHEIM KG (DE) | 1998-02-17 | — | — | US | disclosed |