Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.68 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659053 | 0.90 | SMN1; SMN2 (1.00) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL8577834 | 0.85 | POLB (0.63) | SMN1; SMN2POLB | |
| SCHEMBL15929126 | 0.84 | MTNR1A (0.69) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL11435187 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL12405428 | 0.83 | ACACB (0.71) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL25335984 | 0.83 | CYP2D6 (0.68) | SMN1; SMN2POLB | |
| SCHEMBL16562076 | 0.81 | FPR2 (0.73) | SMN1; SMN2 | |
| SCHEMBL8928104 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL5072982 | 0.81 | POLB (0.58) | SMN1; SMN2MTNR1AMTNR1BPOLB | |
| SCHEMBL29699652 | 0.81 | POLB (0.58) | SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118464-C | Noval pyrimidine derivatives and process and preparing thereof | YUHAN CORP (KR) | 2003-08-20 | — | — | CN | disclosed |
| CN-1251586-A | Noval pyrimidine derivatives and process and preparing thereof | YUHAN CORP (KR) | 2000-04-26 | — | — | CN | disclosed |