Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424541 | 1.00 | CA2 (0.44) | CA2ALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL10423865 | 1.00 | CA2 (0.44) | CA2ALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL20624952 | 0.80 | PABPC1 (0.48) | ALDH1A1KDM4ESMN1; SMN2TMEM97SIGMAR1 | |
| SCHEMBL18069672 | 0.77 | ACE (0.32) | TMEM97SIGMAR1ACE | |
| SCHEMBL10764346 | 0.75 | ADORA3 (0.32) | ADORA3 | |
| Acetic Acid SCHEMBL5708591 | 0.75 | CA2 (0.47) | CA2ALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL17038983 | 0.75 | CA2 (0.47) | CA2ALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL17038984 | 0.75 | CA2 (0.47) | CA2ALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL10424539 | 0.74 | CA2 (0.51) | CA2ALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL10423870 | 0.74 | CA2 (0.51) | CA2ALDH1A1KDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288871-A2 | Pharmaceutical compositions containing thio-dioxolane derivatives having mucolytic activity | PROTER S.p.A. (IT) | 1988-11-02 | — | — | EP | claimed |
| US-4910220-A | Thiomethyl group in position 4 of ring | PROTER SPA (IT) | 1990-03-20 | — | — | US | disclosed |
| EP-0288871-A2 | Pharmaceutical compositions containing thio-dioxolane derivatives having mucolytic activity | PROTER S.p.A. (IT) | 1988-11-02 | — | — | EP | disclosed |