Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815248 | 0.84 | NAAA (0.43) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL27604017 | 0.84 | NAAA (0.43) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL10521419 | 0.83 | MEN1 (0.43) | MMP2MMP9MMP3MMP1MMP14 | |
| Ammonia Solution, Strong SCHEMBL27662920 | 0.82 | PRSS1 (0.46) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL9781115 | 0.82 | PRSS1 (0.43) | MMP2MMP9NAAAPRSS1CTSG | |
| SCHEMBL16468978 | 0.81 | MMP2 (0.44) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL28469779 | 0.81 | ALDH1A1 (0.43) | MMP2MMP9MMP3PRSS1CTSG | |
| SCHEMBL14768367 | 0.79 | MEN1 (0.42) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL27886667 | 0.79 | MEN1 (0.42) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL10430558 | 0.78 | NAAA (0.41) | MMP2MMP9MMP3MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202759-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0202759-A2 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1986-11-26 | — | — | EP | disclosed |