SCHEMBL10424971

SCHEMBL10424971

CC(C)=CCOC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.57
MAPT P10636 1/20 0.50
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP12 P39900 1/20 0.49
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ESR1 P03372 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
ESR2 Q92731 1/20 0.42
CA14 Q9ULX7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid 3-Methyl-2-Butenyl Ester SCHEMBL873002 0.87 TRPV1 (0.55) TRPV1MMP1MMP2MMP9MMP12
SCHEMBL3748244 0.86 ESR1 (0.59) TRPV1MAPTMMP1MMP2MMP9
SCHEMBL28603920 0.86 MMP1 (0.49) TRPV1MMP1MMP2MMP9MMP12
SCHEMBL2456552 0.85 MAPT (0.49) TRPV1MAPTALDH1A1TP53TSHR
SCHEMBL2833266 0.84 TRPV1 (0.56) TRPV1MAPTMMP1MMP2MMP9
SCHEMBL5925543 0.84 LMNA (0.61) TRPV1MAPTMMP1MMP2MMP9
SCHEMBL27759174 0.83 MMP1 (0.51) TRPV1MMP1MMP2MMP9MMP12
SCHEMBL5301347 0.81 ALDH1A1 (0.55) TRPV1MAPTMMP1MMP2MMP9
Benzoic Acid SCHEMBL28235617 0.81 DAO (0.48) TRPV1MMP1MMP2MMP9MMP12
SCHEMBL8855920 0.81 TRPV1 (0.70) TRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4975522-A Crosslinkable compounds and method for making Adademie der Wissenschaften der DDR (DD) 1990-12-04 US disclosed