Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10424444 | 0.98 | LSS (0.36) | CARM1PRMT6HRH3LSSHTR2A | |
| SCHEMBL10460534 | 0.91 | ALOX15 (0.40) | CARM1PRMT6HRH3LSSSLC6A5 | |
| Hydrochloric Acid SCHEMBL10424978 | 0.90 | ALOX15 (0.39) | CARM1PRMT6HRH3LSSSLC6A5 | |
| Hydrochloric Acid SCHEMBL10424434 | 0.90 | ALOX15 (0.39) | CARM1PRMT6HRH3LSSSLC6A5 | |
| SCHEMBL10423372 | 0.79 | ALOX15 (0.40) | CARM1PRMT6HRH3HTR2A | |
| SCHEMBL10423406 | 0.78 | HRH3 (0.47) | CARM1PRMT6HRH3 | |
| SCHEMBL10423401 | 0.78 | CARM1 (0.58) | CARM1PRMT6HRH3 | |
| SCHEMBL10423366 | 0.76 | HRH3 (0.42) | HRH3SLC6A3KCNH2 | |
| SCHEMBL24351019 | 0.74 | LMNA (0.36) | CARM1PRMT6HRH3SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL10424431 | 0.74 | SMN1; SMN2 (0.41) | HRH3SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4954511-A | ALLEVIATING PAIN, TREATING DEPRESSION, CONVULSIONS AND HYPERTENSION | HOECHST-ROUSSELL PHARMACEUTICALS INC. (US) | 1990-09-04 | — | — | US | claimed |
| US-4954511-A | ALLEVIATING PAIN, TREATING DEPRESSION, CONVULSIONS AND HYPERTENSION | HOECHST-ROUSSELL PHARMACEUTICALS INC. (US) | 1990-09-04 | — | — | US | disclosed |
| US-4914204-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS, HYPOTENSIVE AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0333027-A1 | 4-Pentafluorophenoxypiperidines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-09-20 | — | — | EP | disclosed |