Ethylene Glycol

Ethylene Glycol

SCHEMBL10425239

CC(=O)c1ccnc(Cl)c1.CCOC(C)OCC.OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 1/20 0.37
RECQL P46063 1/20 0.36
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
TAS1R2 Q8TE23 2/20 0.36
SMARCA2 P51531 3/20 0.35
SMARCA4 P51532 2/20 0.35
ALDH1A1 P00352 3/20 0.34
MAPK1 P28482 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
HIF1A Q16665 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
PREP P48147 1/20 0.34
FAP Q12884 1/20 0.34
AAK1 Q2M2I8 1/20 0.34
MAPK14 Q16539 1/20 0.34
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29640105 0.80 SMARCA2 (0.49) RECQLTAS1R3TAS1R1TAS1R2SMARCA2
SCHEMBL364320 0.80 SMARCA2 (0.49) RECQLTAS1R3TAS1R1TAS1R2SMARCA2
Bromide SCHEMBL3611932 0.78 SMARCA2 (0.47) RECQLTAS1R3TAS1R1TAS1R2SMARCA2
Ethyl-2-Chloropyridine-4-Carboxylate SCHEMBL1425666 0.71 JMJD6 (0.56) ALDH1A1CA12CA9MAOA
Alcohol SCHEMBL28687926 0.70 KDM5B (0.52) RECQLTAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL4691080 0.69 JMJD6 (0.37) RECQLTAS1R3TAS1R1TAS1R2SMARCA2
Acetone SCHEMBL16666366 0.69 LMNA (0.60) ALDH1A1TSHR
SCHEMBL5860112 0.69 TAS1R3 (0.44) RECQLTAS1R3TAS1R1TAS1R2SMARCA2
Acetophenone SCHEMBL6684394 0.69 LMNA (0.47) ALDH1A1MEN1KMT2AMAOB
SCHEMBL27953096 0.68 JMJD6 (0.56) TAS1R3TAS1R1TAS1R2ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4966971-A REDUCTION, HYDROLYSIS, CYCLIZATION OF ACETAL COMPOUND CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 1990-10-30 US disclosed