Acetone

Acetone

SCHEMBL16666366

CC(C)=O.CCOC(C)OCC.OCCO

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.60
ALDH1A1 P00352 6/20 0.36
HSD17B10 Q99714 1/20 0.36
THRB P10828 1/20 0.35
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 2/20 0.31
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL590699 0.92 LMNA (0.71) LMNAALDH1A1HSD17B10THRBTDP1
Ethylene Glycol SCHEMBL356222 0.89 LMNA (0.75) LMNAALDH1A1THRBTDP1TSHR
Acetone SCHEMBL3833129 0.87 LMNA (0.63) LMNAALDH1A1HSD17B10THRBTDP1
Acetone SCHEMBL1036956 0.87 LMNA (0.63) LMNAALDH1A1HSD17B10THRBTDP1
Ethylene Glycol SCHEMBL9004515 0.87 LMNA (0.63) LMNAALDH1A1THRBPPARD
Propylene Glycol SCHEMBL1532415 0.86 LMNA (0.55) LMNAALDH1A1HSD17B10THRBTDP1
Acetic Acid SCHEMBL23907968 0.84 LMNA (0.67) LMNAALDH1A1HSD17B10THRBTDP1
Acetic Acid SCHEMBL222953 0.84 LMNA (0.67) LMNAALDH1A1HSD17B10THRBTDP1
Butanedione SCHEMBL4368674 0.84 LMNA (0.67) LMNAALDH1A1HSD17B10THRBTDP1
Acetic Acid SCHEMBL8529879 0.82 LMNA (0.63) LMNAALDH1A1HSD17B10THRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933230-B1 ORGANIC SOLVENT DISPERSION OF TITANIUM OXIDE SOLID-SOLUTION PARTICLES, MAKING METHOD AND COATING COMPOSITION SHINETSU CHEMICAL CO (JP) 2018-01-03 EP disclosed
EP-2865720-B1 Photocurable coating composition, laminate, and automotive headlamp covering sheet SHINETSU CHEMICAL CO (JP) 2017-05-03 EP disclosed
EP-2868717-B1 Titania-containing coating composition and coated article SHINETSU CHEMICAL CO (JP) 2017-04-19 EP disclosed
EP-2952480-A1 TITANIUM OXIDE SOLID SOLUTION DISPERSION AND COATING COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2015-12-09 EP disclosed
US-20150299417-A1 ORGANIC SOLVENT DISPERSION OF TITANIUM OXIDE SOLID-SOLUTION PARTICLES, MAKING METHOD, AND COATING COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-22 US disclosed
EP-2933230-A1 ORGANIC SOLVENT DISPERSION OF TITANIUM OXIDE SOLID-SOLUTION PARTICLES, MAKING METHOD AND COATING COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2015-10-21 EP disclosed
US-20150125707-A1 TITANIA-CONTAINING COATING COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-07 US disclosed
EP-2868717-A1 Titania-containing coating composition and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-06 EP disclosed
US-20150118483-A1 PHOTOCURABLE COATING COMPOSITION, LAMINATE, AND AUTOMOTIVE HEADLAMP COVERING SHEET SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-04-30 US disclosed
EP-2865720-A1 Photocurable coating composition, laminate, and automotive headlamp covering sheet Shin-Etsu Chemical Co., Ltd. (JP) 2015-04-29 EP disclosed