Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685441 | 0.84 | MEN1 (0.48) | MEN1KMT2ANPC1ATMNPSR1 | |
| SCHEMBL13248622 | 0.75 | SLC6A2 (0.40) | MEN1KMT2ALMNASLC6A2SLC6A4 | |
| SCHEMBL3401038 | 0.75 | LMNA (0.41) | MEN1KMT2ANPC1LMNA | |
| SCHEMBL8609442 | 0.75 | LMNA (0.45) | MEN1KMT2ANPC1LMNAPOLB | |
| SCHEMBL12238644 | 0.72 | CYP2C19 (0.44) | MEN1KMT2A | |
| SCHEMBL27976218 | 0.72 | CYP2C19 (0.44) | MEN1KMT2ALMNA | |
| SCHEMBL29103156 | 0.72 | MEN1 (0.47) | MEN1KMT2ANPC1ATMPOLB | |
| SCHEMBL28671153 | 0.70 | CYP2C19 (0.36) | MEN1KMT2ANPC1ATMLMNA | |
| SCHEMBL6930326 | 0.69 | MEN1 (0.49) | MEN1KMT2ANPC1ATMLMNA | |
| SCHEMBL6247835 | 0.69 | LMNA (0.47) | MEN1KMT2ANPC1ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268599-B1 | Derivatives of campholenic aldehyde | GIVAUDAN SA (CH) | 2011-09-21 | — | — | EP | disclosed |
| EP-2252674-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-09-07 | — | — | EP | disclosed |
| EP-2268599-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2011-01-05 | — | — | EP | disclosed |