Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042579 | 0.84 | MEN1 (0.45) | MEN1KMT2ANPC1LMNAATM | |
| SCHEMBL6930326 | 0.81 | MEN1 (0.49) | MEN1KMT2ANPC1LMNAATM | |
| SCHEMBL6247835 | 0.81 | LMNA (0.47) | MEN1KMT2ANPC1LMNAATM | |
| SCHEMBL8609442 | 0.79 | LMNA (0.45) | MEN1KMT2ANPC1LMNAPOLB | |
| SCHEMBL3401038 | 0.79 | LMNA (0.41) | MEN1KMT2ANPC1LMNA | |
| SCHEMBL11575081 | 0.78 | LMNA (0.44) | MEN1KMT2ANPC1LMNAATM | |
| SCHEMBL7914381 | 0.77 | CYP2C19 (0.46) | MEN1KMT2ALMNA | |
| Ammonia Solution, Strong SCHEMBL9711074 | 0.77 | LMNA (0.47) | MEN1KMT2ANPC1LMNAPOLB | |
| Ammonia Solution, Strong SCHEMBL27615501 | 0.77 | LMNA (0.42) | MEN1KMT2ANPC1LMNASMN1; SMN2 | |
| SCHEMBL756001 | 0.77 | LMNA (0.42) | MEN1KMT2ANPC1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063281-A2 | PROCESS FOR THE CHIRAL RESOLUTION OF ACETATES TO (R)-ALCOHOLS EMPLOYING FUSARIUM PROLIFERATUM | Council of Scientific and Industrial Research (IN) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015063796-A2 | A PROCESS OF CHIRAL RESOLUTION OF CYCLIC AND ACYCLIC ACETATES TO ENANTIOMERICALLY PURE (R)--ALCOHOLS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-05-07 | — | — | WO | disclosed |