Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426034 | 1.00 | MAPT (0.35) | MAPTCTSLCTSBCTSSCPB2 | |
| SCHEMBL4519604 | 0.78 | MME (0.36) | — | |
| SCHEMBL7357707 | 0.77 | PPARG (0.36) | MAPTSMN1; SMN2 | |
| SCHEMBL1073717 | 0.77 | ITGB2 (0.36) | CPB2ITGB2ICAM1ITGALCPB1 | |
| SCHEMBL163396 | 0.77 | CPB2 (0.36) | CPB2ITGB2ICAM1ITGALCPB1 | |
| SCHEMBL27547178 | 0.77 | CPB2 (0.36) | CPB2ITGB2ICAM1ITGALCPB1 | |
| SCHEMBL151335 | 0.77 | CPB2 (0.36) | CPB2ITGB2ICAM1ITGALCPB1 | |
| SCHEMBL151334 | 0.77 | CPB2 (0.36) | CPB2ITGB2ICAM1ITGALCPB1 | |
| SCHEMBL5542778 | 0.77 | CPB2 (0.33) | CPB2ITGB2ICAM1ITGALCPB1 | |
| SCHEMBL5542771 | 0.77 | CPB2 (0.33) | CPB2ITGB2ICAM1ITGALCPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898878-A | Antioxidant thiohistidine compounds | THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1990-02-06 | — | — | US | disclosed |