SCHEMBL4519604

SCHEMBL4519604

O=C(O)C(Cc1c[nH]cn1)Nc1ccsc1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 3/20 0.36
▸ GPR142 Q7Z601 1/20 0.30
▸ PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208660 0.83 PPARG (0.40) MMEGPR142PPARG
SCHEMBL11208659 0.83 PPARG (0.40) MMEGPR142PPARG
SCHEMBL7357707 0.80 PPARG (0.36) PPARG
SCHEMBL10425835 0.78 MAPT (0.35) —
SCHEMBL10845741 0.78 CYP2C19 (0.36) —
SCHEMBL497463 0.78 CYP2C19 (0.36) —
SCHEMBL10426034 0.78 MAPT (0.35) —
SCHEMBL8772935 0.77 FPR2 (0.44) PPARG
Methane SCHEMBL28061561 0.77 CYP2C19 (0.35) —
SCHEMBL8772938 0.77 FPR2 (0.44) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3546066-B1 AMPHOTERIC DISSOCIATION ION EXCHANGE MEDIUM, ITS USE, AND SEPARATION CAPACITY CALIBRATION METHOD CHONGQING BOLANYING BLY BIOTECHNOLOGY CO LTD CHINA (CN) 2021-01-20 — — EP claimed
US-20190291095-A1 AMPHOTERIC DISSOCIATION ION EXCHANGE MEDIUM AND USES THEREOF AND METHOD FOR CALIBRATING SEPARATION CAPACITY THEREOF CHONGQING BOLANYING BLY BIOTECHNOLOGY CO LTD (CN) 2019-09-26 — — US claimed
US-20090227597-A1 PYRAZOLOPYRIMIDINONES AS PHOSPHODIESTERASE INHIBITORS CTG PHARMA S.R.L. (IT) 2009-09-10 — — US claimed
US-11358136-B2 Amphoteric dissociation ion exchange medium and uses thereof and method for calibrating separation capacity thereof CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) 2022-06-14 — — US disclosed
EP-3546066-B1 AMPHOTERIC DISSOCIATION ION EXCHANGE MEDIUM, ITS USE, AND SEPARATION CAPACITY CALIBRATION METHOD CHONGQING BOLANYING BLY BIOTECHNOLOGY CO LTD CHINA (CN) 2021-01-20 — — EP disclosed
US-20200376480-A1 AMPHOTERIC DISSOCIATION ION EXCHANGE MEDIUM AND USES THEREOF AND METHOD FOR CALIBRATING SEPARATION CAPACITY THEREOF CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) 2020-12-03 — — US disclosed
EP-3546066-A1 AMPHOTERIC DISSOCIATION ION EXCHANGE MEDIUM, APPLICATION METHOD, AND SEPARATION CAPACITY CALIBRATION METHOD Chongqing Bolanying (BLY) Biotechnology Co., Ltd., China (CN) 2019-10-02 — — EP disclosed
US-20190291095-A1 AMPHOTERIC DISSOCIATION ION EXCHANGE MEDIUM AND USES THEREOF AND METHOD FOR CALIBRATING SEPARATION CAPACITY THEREOF CHONGQING BOLANYING BLY BIOTECHNOLOGY CO LTD (CN) 2019-09-26 — — US disclosed
CN-108097336-B Both sexes dissociating ions exchange media, application method and separation capacity scaling method 重庆博蓝鹰生物技术有限公司 2019-02-26 — — CN disclosed
CN-108097336-A Both sexes dissociating ions exchange media, application process and separation capacity scaling method 重庆博蓝鹰生物技术有限公司 2018-06-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227597-A1 PYRAZOLOPYRIMIDINONES AS PHOSPHODIESTERASE INHIBITORS PDE3A, PDE3B, PDE2A MME 4270/4885GPR142 96/4885PPARG 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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