Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPR3 | P17342 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208659 | 0.88 | PPARG (0.40) | PPARGGAAMAPTITGB1ITGA4 | |
| SCHEMBL11208660 | 0.88 | PPARG (0.40) | PPARGGAAMAPTITGB1ITGA4 | |
| SCHEMBL8772938 | 0.86 | FPR2 (0.44) | PPARGITGB1ITGA4SMN1; SMN2KMT2A | |
| SCHEMBL8772935 | 0.86 | FPR2 (0.44) | PPARGITGB1ITGA4SMN1; SMN2KMT2A | |
| SCHEMBL9828758 | 0.82 | PIN1 (0.43) | CA1SMN1; SMN2KMT2A | |
| SCHEMBL9828763 | 0.82 | PIN1 (0.43) | CA1SMN1; SMN2KMT2A | |
| SCHEMBL9221798 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1MAPTPOLBMMP9 | |
| SCHEMBL29086848 | 0.80 | TRHDE (0.43) | PPARGGAAL3MBTL1MAPTPOLB | |
| SCHEMBL6514467 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1MAPTPOLBMMP9 | |
| SCHEMBL5173100 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1MAPTPOLBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |