Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424669 | 0.84 | UBE2T (0.59) | NPC1UBE2TASIC3KMT2AL3MBTL1 | |
| Fluoride SCHEMBL2461456 | 0.83 | UBE2T (0.58) | NPC1UBE2TASIC3KMT2AL3MBTL1 | |
| SCHEMBL2246310 | 0.83 | MMP13 (0.57) | NPC1KMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10665745 | 0.81 | MMP13 (0.55) | NPC1KMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10664215 | 0.81 | MMP13 (0.55) | NPC1KMT2AL3MBTL1ALDH1A1MEN1 | |
| Benzo[D]Thiazole SCHEMBL25268972 | 0.74 | ALDH1A1 (0.54) | NPC1UBE2TASIC3KMT2AL3MBTL1 | |
| Benzoic Acid SCHEMBL4301703 | 0.72 | SMN1; SMN2 (0.51) | NPC1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL620659 | 0.72 | UBE2T (0.59) | NPC1UBE2TASIC3KMT2AL3MBTL1 | |
| SCHEMBL28444199 | 0.70 | MMP13 (0.45) | NPC1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6001358 | 0.69 | UBE2T (0.56) | NPC1UBE2TASIC3KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952513-A | NOT FOR KETONES AND ALDEHYDES; FORMING REACTION PRODUCT IN SITU WITH DERIVATIZING AGENT | CRYSTAL DIAGNOSTICS, INC. (US) | 1990-08-28 | — | — | US | disclosed |