SCHEMBL1042641

SCHEMBL1042641

C[Si](C)(C)c1ccc([O])cc1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
ACHE P22303 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL586534 0.83 NR1H2 (0.50) NR1H2NR1H3ACHEHPGD
SCHEMBL10997473 0.73 NR1H2 (0.44) NR1H2NR1H3ACHEHPGD
SCHEMBL987122 0.71 ACHE (0.53) NR1H2NR1H3ACHEHPGD
Benzoquinone SCHEMBL739813 0.71
SCHEMBL7630021 0.69 NR1H2 (0.37) NR1H2NR1H3ACHEHPGD
SCHEMBL20010800 0.69 CES2 (0.52) NR1H2NR1H3ACHEHPGD
SCHEMBL926572 0.69 CYP2A6 (0.52)
SCHEMBL17492039 0.69 NR1H2 (0.41) NR1H2NR1H3
SCHEMBL1172568 0.69 MEN1 (0.50) NR1H2NR1H3ACHE
SCHEMBL6512153 0.69 NR1H2 (0.41) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231497-A1 Silicone resist materials containing polysiloxanes KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-12 EP claimed
WO-2024084974-A1 METHOD FOR PRODUCING CYCLIC OLEFIN COPOLYMER ポリプラスチックス株式会社 2024-04-25 WO disclosed
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 US disclosed
EP-2272852-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex Sumitomo Chemical Company, Limited (JP) 2011-01-12 EP disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1683802-A1 TRANSITION METAL COMPLEX LIGAND AND OLEFIN POLYMERIZATION CATALYST CONTAINING TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed
US-5198520-A Photoresists KABUSHIKI KAISHA TOSHIBA (JP) 1993-03-30 US disclosed
EP-0493367-A2 Silicone resist materials containing polysilanes and methods of making the same KABUSHIKI KAISHA TOSHIBA (JP) 1992-07-01 EP disclosed
US-5017453-A Integrated circuits KABUSHIKI KAISHA TOSHIBA (JP) 1991-05-21 US disclosed
US-4822716-A FINE PATTERN SEMICONDUCTOR, INTEGRATED CIRCUIT KABUSHIKI KAISHA TOSHIBA (JP) 1989-04-18 US disclosed
EP-0231497-A1 Silicone resist materials containing polysiloxanes KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 NR1H2 412/4885NR1H3 238/4885ACHE 4428/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 NR1H2 412/4885NR1H3 238/4885ACHE 4428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.