Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MAPK10 | P53779 | 12/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355121 | 0.87 | MAPK10 (0.80) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL30979840 | 0.87 | MAPK10 (0.80) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL30597523 | 0.85 | ALDH1A1 (0.79) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL28931630 | 0.85 | ALDH1A1 (0.79) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL17144905 | 0.84 | ALDH1A1 (0.71) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL31011321 | 0.84 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL28180887 | 0.84 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL30439351 | 0.82 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL29010990 | 0.82 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPK10CA1CA2 | |
| SCHEMBL7109609 | 0.80 | LMNA (0.78) | ALDH1A1LMNAMAPK10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351399-A1 | ISOQUINOLINE DERIVATIVES, THEIR MANUFACTURE AND USE | HUHTAMÄKI OY (FI) | 1990-01-24 | — | — | EP | disclosed |
| WO-1988007041-A1 | ISOQUINOLINE DERIVATIVES, THEIR MANUFACTURE AND USE | Huhtamäki Oy (FI) | 1988-09-22 | — | — | WO | disclosed |