Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 12/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | RAD52 | P43351 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.66 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.62 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979840 | 1.00 | MAPK10 (0.80) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL7109609 | 0.89 | LMNA (0.78) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL11719015 | 0.89 | MAPK10 (0.65) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL11715443 | 0.89 | MAPK10 (0.65) | MAPK10LMNAALDH1A1PKMRAD52 | |
| Hydrochloric Acid SCHEMBL11713492 | 0.88 | MAPK10 (0.63) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL28931630 | 0.87 | ALDH1A1 (0.79) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL30597523 | 0.87 | ALDH1A1 (0.79) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL10426643 | 0.87 | ALDH1A1 (0.74) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL17144905 | 0.85 | ALDH1A1 (0.71) | MAPK10LMNAALDH1A1PKMRAD52 | |
| SCHEMBL31011321 | 0.85 | ALDH1A1 (0.76) | MAPK10LMNAALDH1A1PKMRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108239029-A | The preparation of tetrahydroisoquinoliderivatives compound and its salt and medical usage | 中国医学科学院药物研究所 | 2018-07-03 | — | — | CN | claimed |
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-08-19 | — | — | US | disclosed |
| CN-118272274-B | Lactic acid bacteria starter and application thereof in preparation of blueberry corn peptide fermentation liquor | 齐齐哈尔大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118272274-A | Lactic acid bacteria starter and application thereof in preparation of blueberry corn peptide fermentation liquor | 齐齐哈尔大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-118146154-A | Method for synergistic catalysis of selective oxidative dehydrogenation of tetrahydroisoquinoline | 西安石油大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-111689929-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2024-05-31 | — | — | CN | disclosed |
| EP-4295841-A2 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3892610-B1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | SCRIPPS RESEARCH INST (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-111303145-B | Small molecule fluorescent probe and application thereof in chromosome analysis and cytogenetics | 陈斯杰 | 2023-02-28 | — | — | CN | disclosed |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-10-06 | — | — | US | disclosed |
| US-6818651-B2 | ANTIINFLAMMATORY, ANTIASTHMATIC, SKIN, AND AUTOIMMUNE DISORDERS; CROHN*S DISEASE, ULCERATIVE COLITIS, CONJUCTIVITIS, MULTIPLE SCLEROSIS, AND RHEUMATOID ARTHRITIS; CHRONIC OBSTRUCTIVE PULMONARY DISEASE | ALTANA PHARMA AG (DE) | 2004-11-16 | — | — | US | disclosed |
| US-20040044212-A1 | (Dihydro) Isoquinoline derivatives as phosphodiesterase inhibitors | ALTANA PHARMA AG (DE) | 2004-03-04 | — | — | US | disclosed |
| EP-1337515-A1 | (DIHYDRO)ISOQUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2003-08-27 | — | — | EP | disclosed |
| EP-1117627-B1 | TRANSFER HYDROGENATION PROCESS | AVECIA LTD (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2003013545-A1 | NOVEL BENZO-FUSED HETEROCYCLES AS ENDOTHELIN ANTAGONISITS | ACTELION PHARMACEUTICALS LTD (CH) | 2003-02-20 | — | — | WO | disclosed |
| US-6509467-B1 | Of iminium salts using transition metal complex catalyst | AVECIA LIMITED (GB) | 2003-01-21 | — | — | US | disclosed |
| WO-2002040450-A1 | (DIHYDRO)ISOQUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | ALTANA PHARMA AG (DE) | 2002-05-23 | — | — | WO | disclosed |
| WO-2002040449-A1 | DIHYDROISOQUINOLINES AS NOVEL PHOSPHODIESTERASE INHIBITORS | ALTANA PHARMA AG (DE) | 2002-05-23 | — | — | WO | disclosed |
| EP-1117627-A1 | TRANSFER HYDROGENATION PROCESS | Avecia Limited (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018708-A1 | TRANSFER HYDROGENATION PROCESS | AVECIA LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | GRB2, SCTR, OGFR | MAPK10 3329/4885LMNA 4654/4885ALDH1A1 4622/4885 |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | QSOX1, YBX1, SFXN1 | MAPK10 3572/4885LMNA 3340/4885ALDH1A1 3604/4885 |
| US-20040044212-A1 | (Dihydro) Isoquinoline derivatives as phosphodiesterase inhibitors | PDE7B, PDE3B, PDE3A | MAPK10 1836/4885LMNA 1790/4885ALDH1A1 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.