Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426600 | 0.87 | ACHE (0.78) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL10426667 | 0.82 | ACHE (0.83) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL10425830 | 0.81 | ACHE (0.91) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL8342390 | 0.80 | ACHE (0.79) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL8342391 | 0.80 | ACHE (0.79) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL10975569 | 0.79 | ACHE (0.56) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL10970986 | 0.79 | ACHE (0.80) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL10785228 | 0.78 | ACHE (0.55) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL10781928 | 0.78 | ACHE (0.72) | ACHEHRH2MEN1SLC22A1ABCB11 | |
| SCHEMBL4344477 | 0.78 | ACHE (0.90) | ACHEHRH2MEN1SLC22A1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904792-A | N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4760075-A | Miticides | ELI LILLY AND COMPANY (US) | 1988-07-26 | — | — | US | disclosed |