Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940900 | 0.98 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10427163 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL212008 | 0.94 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14993242 | 0.92 | TSHR (0.63) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL670913 | 0.92 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL673043 | 0.92 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL671674 | 0.92 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11420004 | 0.91 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7646477 | 0.91 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL491146 | 0.91 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939218-A | Sulfur-containing aliphatic acrylic compound, crosslinked polymer article, and lens | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-07-03 | — | — | US | disclosed |