Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 4/20 | 0.30 |
| ▸ | CES1 | P23141 | 4/20 | 0.30 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10427136 | 0.98 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10427163 | 0.94 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL491146 | 0.93 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11420004 | 0.93 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7646477 | 0.93 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL212008 | 0.92 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14993242 | 0.90 | TSHR (0.63) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9073332 | 0.90 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL673043 | 0.90 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL670913 | 0.90 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260140398-A1 | OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2026-05-21 | — | — | US | disclosed |
| EP-4603522-A1 | OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2025-08-20 | — | — | EP | disclosed |
| CN-114829539-B | Photochromic curable composition and photochromic optical article | 株式会社德山 | 2024-09-06 | — | — | CN | disclosed |
| CN-114846047-B | Moisture-curable polyurethane composition and laminate | 株式会社德山 | 2024-08-30 | — | — | CN | disclosed |
| CN-111936524-B | Photochromic curable composition | 株式会社德山 | 2022-09-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260140398-A1 | OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | CRYAA, FEM1B, MAPRE1 | TSHR 4218/4885THRB 3916/4885POLB 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.