Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | CES2 | O00748 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491146 | 1.00 | TSHR (0.69) | TSHRCES2THRBPOLBGMNN | |
| SCHEMBL11420004 | 1.00 | TSHR (0.69) | TSHRCES2THRBPOLBGMNN | |
| SCHEMBL11420243 | 0.93 | TSHR (0.62) | TSHRCES2THRBPOLBGMNN | |
| SCHEMBL10427136 | 0.91 | TSHR (0.53) | TSHRCES2THRBPOLBGMNN | |
| SCHEMBL10427163 | 0.88 | TSHR (0.53) | TSHRCES2THRBPOLBAPEX1 | |
| SCHEMBL10150598 | 0.86 | TSHR (0.56) | TSHRTHRBPOLBACHEAPEX1 | |
| SCHEMBL10340003 | 0.86 | CES2 (0.48) | TSHRCES2THRBPOLBGMNN | |
| SCHEMBL212008 | 0.86 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28121972 | 0.85 | TSHR (0.51) | TSHRCES2THRBPOLBAPEX1 | |
| SCHEMBL14993242 | 0.84 | TSHR (0.63) | TSHRCES2THRBPOLBGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100911-A1 | RESIN COMPOSITIONS, AND OPTICAL LENS PREPARED THEREBY | DOOSAN CORPORATION ELECTRO-MATERIALS BG (KR) | 2002-12-19 | — | — | WO | disclosed |