Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745254 | 0.74 | NPSR1 (0.50) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL29661169 | 0.74 | NPSR1 (0.50) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL27971438 | 0.71 | NPSR1 (0.47) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL20787377 | 0.71 | NPSR1 (0.47) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL10909881 | 0.71 | NPSR1 (0.47) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL11073092 | 0.71 | L3MBTL1 (0.47) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL9171286 | 0.71 | NPSR1 (0.47) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL11291646 | 0.71 | NPSR1 (0.47) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL866472 | 0.71 | NPSR1 (0.47) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL17033019 | 0.70 | ALDH1A1 (0.42) | HTR2AHTR2CHTR2BSIGMAR1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945168-A | Method of preparing aryl-(1-phthalimido)-alkyl ketones | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1990-07-31 | — | — | US | disclosed |
| EP-0304018-A2 | Process for the preparation of aryl-(1-phthalimido)alkyl ketones | Degussa Aktiengesellschaft (DE) | 1989-02-22 | — | — | EP | disclosed |