SCHEMBL11073092

SCHEMBL11073092

CC1(O)Cc2ccccc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
LMNA P02545 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
CASP1 P29466 1/20 0.45
CA7 P43166 1/20 0.45
RECQL P46063 1/20 0.45
BACE1 P56817 1/20 0.45
CA9 Q16790 1/20 0.45
EHMT2 Q96KQ7 1/20 0.45
POLB P06746 1/20 0.43
HTR2A P28223 2/20 0.41
HTR2C P28335 2/20 0.41
HTR2B P41595 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8000122 0.81 SIGMAR1 (0.54) L3MBTL1ALDH1A1CA1CA2TSHR
SCHEMBL25835259 0.80 POLB (0.51) L3MBTL1LMNANPSR1HTTALDH1A1
SCHEMBL12822665 0.80 POLB (0.51) L3MBTL1LMNANPSR1HTTALDH1A1
SCHEMBL29661169 0.79 NPSR1 (0.50) L3MBTL1LMNANPSR1HTTALDH1A1
SCHEMBL1745254 0.79 NPSR1 (0.50) L3MBTL1LMNANPSR1HTTALDH1A1
SCHEMBL3994729 0.79 L3MBTL1 (0.50) L3MBTL1LMNANPSR1HTTALDH1A1
SCHEMBL14922392 0.76 PDK2 (0.41) LMNAALDH1A1POLBHTR2AKDM4E
SCHEMBL26983104 0.76 L3MBTL1 (0.47) L3MBTL1LMNANPSR1HTTALDH1A1
SCHEMBL11291646 0.76 NPSR1 (0.47) L3MBTL1LMNANPSR1HTTALDH1A1
SCHEMBL20787377 0.76 NPSR1 (0.47) L3MBTL1LMNANPSR1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106748693-B A kind of synthetic method of alpha-hydroxyacetone compounds 浙江新和成股份有限公司 2019-09-20 CN disclosed
CN-106748693-A A kind of synthetic method of α hydroxyacetone compounds 浙江新和成股份有限公司 2017-05-31 CN disclosed
CN-104710256-B Cheap and efficient synthesis method of alpha-hydroxyketone compound 北京大学 2017-03-22 CN disclosed
CN-104710256-A Cheap and efficient synthesis method of alpha-hydroxyketone compound UNIV BEIJING 2015-06-17 CN disclosed
CN-103613478-B Synthetic method of alpha-hydroxyl carbonyl compound UNIV BEIJING 2015-05-06 CN disclosed
CN-103613478-A Synthetic method of alpha-hydroxyl carbonyl compound UNIV BEIJING 2014-03-05 CN disclosed
EP-0003002-B1 USE OF AROMATIC-ALIPHATIC KETONES AS PHOTOINITIATORS, PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH KETONES AND AROMATIC-ALIPHATIC KETONES CIBA-GEIGY AG (CH) 1984-06-13 EP disclosed
US-4321118-A Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4318791-A PHOTOPOLYMERIZABLE SYSTEM FOR INKS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US disclosed
EP-0003002-A2 Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed