Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.84 |
| ▸ | DRD3 | P35462 | 5/20 | 0.84 |
| ▸ | DRD1 | P21728 | 2/20 | 0.84 |
| ▸ | DRD4 | P21917 | 2/20 | 0.84 |
| ▸ | DRD5 | P21918 | 2/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.84 |
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.84 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.84 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.84 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.82 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.70 |
| ▸ | IGF1R | P08069 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11514533 | 0.98 | DRD2 (0.82) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL29368857 | 0.92 | DRD2 (1.00) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL467093 | 0.92 | DRD2 (1.00) | DRD2DRD3DRD1DRD4DRD5 | |
| Bromide SCHEMBL1321255 | 0.90 | KDM4E (1.00) | DRD2DRD3DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL4305739 | 0.90 | DRD2 (0.96) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL6674754 | 0.86 | DRD2 (0.87) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL9504438 | 0.85 | ADRA1D (0.69) | DRD2DRD3DRD1DRD4DRD5 | |
| Bromide SCHEMBL10744684 | 0.84 | KDM4E (0.88) | DRD2DRD3DRD1DRD4DRD5 | |
| Dopamine SCHEMBL14919131 | 0.84 | DRD2 (0.84) | DRD2DRD3DRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL9504430 | 0.84 | ADRA1D (0.68) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608391-A | NERUOUS SYSTEM DISORDERS, PARKINSON$S DISEASE | CORNELL RESEARCH FOUNDATION INC. (US) | 1986-08-26 | — | — | US | claimed |
| US-4175136-A | N-Phenethyl-N-propyl-3,4-dihydroxyphenethylamines and salts thereof | ROUSSEL UCLAF (FR) | 1979-11-20 | — | — | US | claimed |
| EP-0187019-B1 | IMPROVEMENTS IN OR RELATING TO DOBUTAMINE SALTS | ELI LILLY AND COMPANY (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4175136-A | N-Phenethyl-N-propyl-3,4-dihydroxyphenethylamines and salts thereof | ROUSSEL UCLAF (FR) | 1979-11-20 | — | — | US | disclosed |
| US-4175136-A | N-Phenethyl-N-propyl-3,4-dihydroxyphenethylamines and salts thereof | ROUSSEL UCLAF (FR) | 1979-11-20 | — | — | US | disclosed |
| US-4175136-A | N-Phenethyl-N-propyl-3,4-dihydroxyphenethylamines and salts thereof | ROUSSEL UCLAF (FR) | 1979-11-20 | — | — | US | disclosed |