Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322096 | 0.86 | MCL1 (0.62) | MCL1ALDH1A1LMNAHTTGAA | |
| SCHEMBL3906747 | 0.81 | MCL1 (0.56) | MCL1ALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL10428283 | 0.80 | MCL1 (0.57) | MCL1ALDH1A1CYP3A4HSD17B10GAA | |
| SCHEMBL6217575 | 0.79 | MCL1 (0.74) | MCL1ALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL319941 | 0.75 | — | — | |
| SCHEMBL21227418 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2AANPEPDNPEPCHRNB2 | |
| SCHEMBL3901466 | 0.75 | MCL1 (0.58) | MCL1ALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL8536470 | 0.75 | MCL1 (0.53) | MCL1ALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL3911970 | 0.74 | MCL1 (0.68) | MCL1ALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL7620131 | 0.74 | MCL1 (0.68) | MCL1ALDH1A1CYP3A4HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948879-A | Monoazo compounds containing a fiber-reactive group and an oxazolopyridone or oxazinopyridone coupling component | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |