Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23509372 | 0.81 | KMT2A (0.61) | BCHEL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL278630 | 0.81 | CASR (0.58) | L3MBTL1MEN1KMT2ACASRTDP1 | |
| SCHEMBL23509371 | 0.80 | MEN1 (0.56) | BCHEADRB2ADRB1NR3C1CYP2D6 | |
| Hydrochloric Acid SCHEMBL14343449 | 0.79 | CASR (0.57) | L3MBTL1MEN1KMT2ACASRTDP1 | |
| SCHEMBL12890742 | 0.79 | LMNA (0.49) | L3MBTL1MEN1KMT2A | |
| SCHEMBL3271284 | 0.78 | SIGMAR1 (0.48) | CYP2D6CASRNPSR1 | |
| SCHEMBL22928989 | 0.77 | SLC2A1 (0.42) | BCHECYP2D6L3MBTL1CASR | |
| SCHEMBL9781350 | 0.77 | MEN1 (0.46) | ADRB2ADRB1NR3C1CYP2D6ADRA1A | |
| SCHEMBL2450970 | 0.76 | BCHE (0.71) | BCHEMEN1KMT2ANPSR1 | |
| SCHEMBL3589633 | 0.76 | NQO1 (0.50) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897109-A | ACYLAMINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |