Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164692 | 0.92 | ALDH1A1 (0.49) | SIGMAR1LTA4HSMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL3440308 | 0.90 | LOXL2 (0.50) | SIGMAR1LTA4HSMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL8443205 | 0.90 | LMNA (0.48) | SIGMAR1LTA4HSMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL8851013 | 0.90 | SMN1; SMN2 (0.58) | SIGMAR1LTA4HSMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL24999530 | 0.88 | SIGMAR1 (0.41) | SIGMAR1LTA4HSMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL2548456 | 0.88 | PYCR1 (0.48) | SIGMAR1ALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL7855536 | 0.88 | CYP2C19 (0.53) | SMN1; SMN2POLBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL14549210 | 0.88 | TPSAB1 (0.45) | SIGMAR1LTA4HSMN1; SMN2PARP1SLC2A1 | |
| SCHEMBL6613714 | 0.88 | ITGB1 (0.53) | SIGMAR1LTA4HSMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL16869918 | 0.88 | SIGMAR1 (0.50) | SIGMAR1LTA4HALDH1A1LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244918-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
| US-20210388196-A1 | GENE DELIVERY CARRIER | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-12-16 | — | — | US | disclosed |
| US-11041069-B2 | Gene delivery carrier | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-22 | — | — | US | disclosed |
| US-20190194444-A1 | GENE DELIVERY CARRIER | POLITECNICO DI MILANO (IT) | 2019-06-27 | — | — | US | disclosed |
| US-20190169084-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | Reiley Pharmaceuticals, Inc. | 2019-06-06 | — | — | US | disclosed |
| US-9365614-B2 | IAP BIR domain binding compounds | PHARMASCIENCE INC. (CA) | 2016-06-14 | — | — | US | disclosed |
| US-20150374858-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | Reiley Pharmaceuticals, Inc. | 2015-12-31 | — | — | US | disclosed |
| US-20140336134-A1 | IAP BIR Domain Binding Compounds | PHARMASCIENCE INC. (CA) | 2014-11-13 | — | — | US | disclosed |
| US-8765681-B2 | IAP BIR domain binding compounds | PHARMASCIENCE INC. (CA) | 2014-07-01 | — | — | US | disclosed |
| US-8754237-B2 | Bifunctional histone deacetylase inhibitors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-17 | — | — | US | disclosed |
| US-20080207525-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents; bioavailability; coupling; chemical intermediates | PHARMASCIENCE INC. (CA) | 2008-08-28 | — | — | US | disclosed |
| US-20080069812-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents | AEGERA THERAPEUTICS, INC. (CA) | 2008-03-20 | — | — | US | disclosed |
| US-6992034-B2 | Catalyst component for olefin polymerization | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2006-01-31 | — | — | US | disclosed |
| US-6939963-B2 | Method for the preparation of selectively-substituted corroles and new substituted corroles | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2005-09-06 | — | — | US | disclosed |
| EP-1411927-A4 | METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES | TECHNION RES & DEV FOUNDATION (IL) | 2005-04-20 | — | — | EP | disclosed |
| US-20050009690-A1 | Catalyst component for olefin polymerization | FORMOSA PLASTICS CORPORATIONS, U.S.A. | 2005-01-13 | — | — | US | disclosed |
| US-20040180872-A1 | Use as catalyst , in photovoltaic cells, drugs for diagnosis and photodynamic treatment of tumors or as chemical intermediates; metal complexes of 2,17-Bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrole | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2004-09-16 | — | — | US | disclosed |
| EP-1411927-A1 | METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES | Technion Research and Development Foundation Ltd. (IL) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003004021-A1 | METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2003-01-16 | — | — | WO | disclosed |
| US-3943158-A | POLYURETHANE MONOMERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194444-A1 | GENE DELIVERY CARRIER | PAICS, PBDC1, BCAT1 | SIGMAR1 4663/4885LTA4H 1361/4885SMN1; SMN2 3124/4885 |
| US-20140336134-A1 | IAP BIR Domain Binding Compounds | BIRC2, BIRC7, BIRC5 | SIGMAR1 4744/4885LTA4H 3443/4885SMN1; SMN2 2818/4885 |
| US-11041069-B2 | Gene delivery carrier | PAICS, PBDC1, BCAT1 | SIGMAR1 4663/4885LTA4H 1361/4885SMN1; SMN2 3124/4885 |
| US-20150374858-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | PTGES3, PTGES, HPGDS | SIGMAR1 76/4885LTA4H 32/4885SMN1; SMN2 4033/4885 |
| US-20080069812-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents | BIRC5, XIAP, BIRC2 | SIGMAR1 4339/4885LTA4H 4702/4885SMN1; SMN2 1543/4885 |
| US-20210388196-A1 | GENE DELIVERY CARRIER | PAICS, PBDC1, BCAT1 | SIGMAR1 4663/4885LTA4H 1361/4885SMN1; SMN2 3124/4885 |
| US-20190169084-A1 | CONJUGATES DERIVED FROM NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND METHODS OF USE THEREOF IN IMAGING | PTGES3, PTGES, HPGDS | SIGMAR1 76/4885LTA4H 32/4885SMN1; SMN2 4033/4885 |
| US-20040180872-A1 | Use as catalyst , in photovoltaic cells, drugs for diagnosis and photodynamic treatment of tumors or as chemical intermediates; metal complexes of 2,17-Bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrole | EPOR, NR2E3, CBR1 | SIGMAR1 197/4885LTA4H 3220/4885SMN1; SMN2 3036/4885 |
| US-20080207525-A1 | Inhibitors of apoptosis proteins (IAP); antiproliferative agents; anticancer agents; bioavailability; coupling; chemical intermediates | BIRC5, XIAP, BAX | SIGMAR1 4230/4885LTA4H 4710/4885SMN1; SMN2 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.