Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226446 | 0.91 | MAPT (0.58) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL23604682 | 0.84 | KDM4E (0.48) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL10428597 | 0.81 | MAPT (0.48) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL8680369 | 0.80 | MAPT (0.39) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9227991 | 0.78 | MAPT (0.45) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9840844 | 0.78 | MAPT (0.48) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9840851 | 0.78 | MAPT (0.48) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9839799 | 0.77 | MAPT (0.55) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL10428734 | 0.77 | MAPT (0.48) | MAPTTHRBKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9230491 | 0.77 | MAPT (0.52) | MAPTTHRBKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4909963-A | Spiro(indole-1,4-benzoxazine) compound | PPG INDUSTRIES, INC. (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0324786-A1 | PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME. | PPG INDUSTRIES INC (US) | 1989-07-26 | — | — | EP | disclosed |
| EP-0324786-A4 | PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME. | PPG INDUSTRIES INC (US) | 1989-06-26 | — | — | EP | disclosed |
| US-4816584-A | Photochromic spiro(indoline)benzoxazines | PPG INDUSTRIES, INC. (US) | 1989-03-28 | — | — | US | disclosed |
| WO-1988002371-A1 | PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME | PPG INDUSTRIES, INC. (US) | 1988-04-07 | — | — | WO | disclosed |