SCHEMBL10429101

SCHEMBL10429101

Fc1cc(F)cc(-c2cc[c]c(Cl)c2Cl)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326833 0.77 RXRA (0.32) AHR
SCHEMBL2011820 0.77 GRM5 (0.32)
SCHEMBL5646728 0.75 AHR (0.43) AHR
SCHEMBL5967116 0.74 AHR (0.59) AHR
SCHEMBL6207069 0.74 CYP2A6 (0.43)
SCHEMBL1135192 0.74
SCHEMBL15638054 0.69 GABRG2 (0.42)
SCHEMBL17514559 0.69
SCHEMBL2015119 0.69 AHR (0.31) AHR
SCHEMBL11322289 0.69 NPC1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106349217-A Serine/threonine kinase inhibitors 阵列生物制药公司 2017-01-25 CN disclosed
US-4952580-A NEMATOCIDES, ANTHELMINTICS FMC CORPORATION (US) 1990-08-28 US disclosed