Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18040335 | 0.85 | LMNA (0.50) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18040336 | 0.85 | LMNA (0.50) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL10920362 | 0.83 | HPGD (0.50) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2317454 | 0.82 | RXRA (0.61) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16143333 | 0.81 | RXRA (0.60) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29085939 | 0.80 | AKR1C3 (0.49) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7237622 | 0.80 | ALDH1A1 (0.63) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7082122 | 0.80 | KDM4E (0.64) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10429197 | 0.80 | GLRA1 (0.64) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15673277 | 0.80 | RXRA (0.62) | SLC6A5HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966855-A | SUBSTITUTED OXAZOLES OR THIAZOLES, FOR DETECTING HYDROGEN PEROXIDE | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-30 | — | — | US | disclosed |
| EP-0167973-B1 | REDOX INDICATORS | Roche Diagnostics GmbH (DE) | 1988-06-22 | — | — | EP | disclosed |