Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27434524 | 0.86 | ALDH1A1 (0.66) | ALDH1A1HPGDARNR5A1 | |
| SCHEMBL28252063 | 0.85 | XDH (0.43) | ALDH1A1HPGDARLTA4HMEN1 | |
| SCHEMBL28419965 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HPGDARXDH | |
| SCHEMBL14228412 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDARGAAMAPT | |
| SCHEMBL10502406 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HPGDARLTA4HXDH | |
| SCHEMBL2774024 | 0.81 | HPGD (0.49) | ALDH1A1HPGDARMEN1NPC1 | |
| SCHEMBL8202547 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDARXDH | |
| SCHEMBL13362524 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDARXDH | |
| SCHEMBL3995606 | 0.80 | LTA4H (0.50) | ALDH1A1LTA4HNR5A1MEN1NPC1 | |
| SCHEMBL13784763 | 0.79 | LTA4H (0.50) | ALDH1A1HPGDARLTA4HNR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931209-A | Liquid crystalline materials and method of making | CRYSTALOID ELECTRONICS, INC. (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0369037-A1 | Liquid crystalline materials and method of making | Crystaloid Electronics Company (US) | 1990-05-23 | — | — | EP | disclosed |