Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271574 | 0.89 | PRKCZ (0.50) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL30189523 | 0.85 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL8879993 | 0.85 | HMGCR (0.49) | ALDH1A1MAPTKDM4EHPGDHMGCR | |
| SCHEMBL9562753 | 0.80 | ADORA3 (0.52) | ALDH1A1MAPTKDM4EHPGDGAA | |
| SCHEMBL2648212 | 0.78 | GCGR (0.62) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL8319524 | 0.78 | SMN1; SMN2 (0.61) | ALDH1A1MAPTKDM4EHPGDGAA | |
| SCHEMBL397192 | 0.77 | ADORA3 (0.60) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL8878404 | 0.77 | HMGCR (0.48) | MAPTKDM4EHPGDHMGCRGCGR | |
| SCHEMBL30189329 | 0.77 | ADORA3 (0.63) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL28335019 | 0.77 | ADORA3 (0.63) | ALDH1A1L3MBTL1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323490-B2 | Pyrrole compounds and uses thereof | AMBIT BIOSCIENCES CORPORATION (US) | 2008-01-29 | — | — | US | disclosed |
| US-4898868-A | ANTICHOLESTEROL AGENTS; LACTONE OR FREE ACID FORM | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-06 | — | — | US | disclosed |