Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde Oxime SCHEMBL10429285 | 1.00 | ALOX15 (0.40) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9661654 | 0.93 | MEN1 (0.42) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10429282 | 0.93 | MEN1 (0.42) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9661940 | 0.84 | TSHR (0.40) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10363571 | 0.77 | ALDH1A1 (0.44) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10547687 | 0.77 | ALDH1A1 (0.44) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10410397 | 0.73 | MEN1 (0.54) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9661641 | 0.73 | MEN1 (0.54) | ALOX15MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9661882 | 0.72 | CYP1A2 (0.53) | ALOX15KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL10410390 | 0.71 | MAPT (0.44) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908363-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |