Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285741 | 0.85 | MAPT (0.46) | TDP1MAPTPOLBCACNA1BAPBA1 | |
| SCHEMBL12658527 | 0.84 | TDP1 (0.35) | TDP1MAPTPOLBCACNA1BAPBA1 | |
| SCHEMBL24326765 | 0.73 | TDP1 (0.43) | TDP1HSD17B10ALDH1A1ADORA1ADORA2A | |
| SCHEMBL33146 | 0.71 | PDE4A (0.48) | TDP1ALDH1A1ADORA1ADORA2AIDH2 | |
| SCHEMBL13295567 | 0.71 | PDE4A (0.39) | TDP1HSD17B10ADORA1ADORA2AIDH2 | |
| SCHEMBL2024856 | 0.71 | HSD17B10 (0.35) | TDP1HSD17B10ADORA1ADORA2ALMNA | |
| SCHEMBL9505994 | 0.70 | CYP1A2 (0.57) | MAPTPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL3675383 | 0.70 | — | — | |
| SCHEMBL9505958 | 0.69 | ADRB3 (0.36) | HPGDALDH1A1L3MBTL1LMNA | |
| SCHEMBL11445700 | 0.69 | MAPT (0.50) | TDP1MAPTPOLBCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0084020-B1 | N-ARYLSULFONYL-N'-PYRIMIDINYL UREAS | CIBA-GEIGY AG (CH) | 1987-09-16 | — | — | EP | disclosed |
| US-4551531-A | PLANT GROWTH REGULATORS, ANTIGROWTH AGENTS, HERBICIDES | CIBA GEIGY CORPORATION (US) | 1985-11-05 | — | — | US | disclosed |
| US-4478635-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| EP-0084020-A2 | N-arylsulfonyl-N'-pyrimidinyl ureas | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | disclosed |