Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11171745 | 0.87 | ALDH1A1 (0.35) | ADRB3EP300KAT2BKAT8HSD17B1 | |
| SCHEMBL2914660 | 0.76 | TSHR (0.56) | TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18719350 | 0.74 | KIF11 (0.38) | KEAP1TSHRNPC1LMNAHPGD | |
| SCHEMBL11170465 | 0.74 | ALDH1A1 (0.40) | KEAP1TSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9507831 | 0.71 | TSHR (0.65) | KEAP1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27519649 | 0.70 | LMNA (0.50) | ALDH1A1SMN1; SMN2HTTNPC1LMNA | |
| SCHEMBL10429480 | 0.69 | TDP1 (0.41) | ALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL10641826 | 0.68 | CA12 (0.39) | KEAP1TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13977617 | 0.68 | KEAP1 (0.40) | KEAP1ALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL9505994 | 0.67 | CYP1A2 (0.57) | TSHRALDH1A1NPC1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0093306-B1 | METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| US-4421601-A | LACQUERS, INKS, PAINTS, TEXTILES, PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-20 | — | — | US | disclosed |
| EP-0093306-A1 | Methods for the preparation of azo compounds, and azo compounds | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |
| US-4014863-A | LACQUERS, PRINTING INKS, PAINTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |