Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13750837 | 0.84 | HTT (0.59) | NPSR1CYP3A4CYP2C9NTSR1CYP2C19 | |
| SCHEMBL9506004 | 0.80 | RAB9A (0.52) | NPSR1KMT2AHTTLMNANPC1 | |
| SCHEMBL10429444 | 0.78 | TSHR (0.65) | NPSR1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10429487 | 0.77 | MAPT (0.64) | NPSR1KMT2AHTTNPC1RAB9A | |
| SCHEMBL23795778 | 0.76 | NPC1 (0.71) | NPSR1HTTLMNANPC1RAB9A | |
| SCHEMBL4544839 | 0.76 | SLC2A1 (0.65) | NPSR1CYP3A4CYP2C9NTSR1CYP2C19 | |
| SCHEMBL4544852 | 0.76 | SLC2A1 (0.65) | NPSR1CYP3A4CYP2C9NTSR1CYP2C19 | |
| SCHEMBL9483332 | 0.76 | NPSR1 (0.54) | NPSR1CYP3A4CYP2C9NTSR1CYP2C19 | |
| SCHEMBL8633131 | 0.76 | HTT (0.51) | NPSR1CYP3A4CYP2C9NTSR1CYP2C19 | |
| SCHEMBL10939229 | 0.76 | TSHR (0.67) | NPSR1CYP3A4CYP2C9NTSR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |