Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564238 | 0.87 | RAPGEF4 (0.61) | RAB9ANPC1HTTRAPGEF4ALDH1A1 | |
| SCHEMBL10429482 | 0.80 | NPSR1 (0.53) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14363158 | 0.79 | NPC1 (0.73) | RAB9ANPC1HTTRAPGEF4ALDH1A1 | |
| SCHEMBL8973681 | 0.79 | NPC1 (0.56) | RAB9ANPC1HTTRAPGEF4ALDH1A1 | |
| SCHEMBL10879967 | 0.79 | RAB9A (0.52) | RAB9ANPC1HTTRAPGEF4ALDH1A1 | |
| SCHEMBL4544857 | 0.76 | KCNH3 (0.53) | RAB9ANPC1HTTRAPGEF4KDM4E | |
| SCHEMBL1334869 | 0.76 | RAPGEF4 (0.74) | RAB9ANPC1HTTRAPGEF4ALDH1A1 | |
| SCHEMBL30320262 | 0.76 | RAPGEF4 (0.74) | RAB9ANPC1HTTRAPGEF4ALDH1A1 | |
| SCHEMBL9507913 | 0.76 | GAA (0.50) | RAB9ANPC1RAPGEF4MAPK1L3MBTL1 | |
| SCHEMBL4544787 | 0.75 | NFKB1 (0.59) | RAB9ANPC1HTTRAPGEF4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0093306-B1 | METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0093306-A1 | Methods for the preparation of azo compounds, and azo compounds | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |