Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665619 | 0.70 | ALDH1A1 (0.49) | KMT2AALDH1A1SMN1; SMN2HSD17B10TP53 | |
| SCHEMBL6493490 | 0.68 | ALDH1A1 (0.55) | KMT2AALDH1A1SMN1; SMN2HSD17B10TP53 | |
| SCHEMBL11443188 | 0.68 | HPGD (0.58) | KMT2AALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL18802950 | 0.65 | GRM5 (0.40) | KMT2AALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL11508684 | 0.64 | KMT2A (0.39) | KMT2AALDH1A1MAPTTSHRHPGD | |
| SCHEMBL8767485 | 0.62 | ALDH1A1 (0.56) | KMT2AALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL8994051 | 0.61 | GSK3B (0.56) | KMT2AALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL1659994 | 0.61 | KDM4E (0.52) | KMT2AALDH1A1SMN1; SMN2HSD17B10TP53 | |
| SCHEMBL4493177 | 0.61 | BACE1 (0.63) | ALDH1A1SMN1; SMN2HSD17B10TP53MAPT | |
| SCHEMBL9920492 | 0.59 | MEN1 (0.68) | KMT2AALDH1A1SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950670-A | Psychological and cardiovascular disorders | SYNTHELABO (FR) | 1990-08-21 | — | — | US | disclosed |