Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17359218 | 0.80 | P2RX7 (0.37) | P2RX7NMT1HTTALOX15GLO1 | |
| SCHEMBL2308076 | 0.78 | TSHR (0.39) | HTTTSHRKMT2AALDH1A1LMNA | |
| SCHEMBL22300096 | 0.77 | TSHR (0.36) | HTTALOX15GLO1TSHRKMT2A | |
| SCHEMBL145899 | 0.76 | KMT2A (0.43) | P2RX7NMT1HTTALOX15GLO1 | |
| SCHEMBL4272874 | 0.76 | ESR2 (0.34) | P2RX7HTTTSHRALDH1A1LMNA | |
| SCHEMBL25043764 | 0.76 | NAPRT (0.41) | HTTGLO1TSHRSLC40A1KMT2A | |
| SCHEMBL15435554 | 0.76 | TSHR (0.42) | HTTTSHRKMT2ATDP1ALDH1A1 | |
| SCHEMBL6589447 | 0.76 | TRIM24 (0.52) | HTTALOX15GLO1TSHRSLC40A1 | |
| SCHEMBL6578328 | 0.76 | BACE1 (0.47) | TSHRSLC40A1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5636862 | 0.76 | SLC22A12 (0.45) | TSHRKMT2ATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936486-B | Heterocyclic compounds comprising pyridine as modulators of IL-12, IL-23 and/or IFN alpha responses | 百时美施贵宝公司 | 2023-09-22 | — | — | CN | claimed |
| CN-108349930-A | Substituted Tricycles and Methods of Use | 艾伯维公司 | 2018-07-31 | — | — | CN | claimed |
| CN-104710355-B | The preparation method and purposes of diphenyl thiourea compounds and its salt of one class containing niacinamide building block | 烟台大学 | 2017-06-16 | — | — | CN | claimed |
| CN-108349930-A | Substituted Tricycles and Methods of Use | 艾伯维公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105121430-B | Conditioning agent for treating the LADA orphan receptor γ related to the biostearin of inflammatory disease (ROR γ) | 葛兰素集团有限公司 | 2017-06-16 | — | — | CN | disclosed |
| CN-104710355-B | The preparation method and purposes of diphenyl thiourea compounds and its salt of one class containing niacinamide building block | 烟台大学 | 2017-06-16 | — | — | CN | disclosed |
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-0376724-A2 | Cephalosporin compounds | TANABE SEIYAKU CO., LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |
| US-4784995-A | BACTERICIDES FOR GRAMPOSITIVE AND GRAMNEGATIVE BACTERIA | TANABE SEIYAKU CO., LTD. (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0250172-A2 | Cephalosporin compounds & processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| US-4690921-A | BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| US-4608373-A | BACTERICIDES, ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-26 | — | — | US | disclosed |
| EP-0142274-A2 | Cephalosporin compounds and salts thereof, their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1985-05-22 | — | — | EP | disclosed |
| EP-0112164-A2 | Cephem compounds, and their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |