Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | PLK1 | P53350 | 2/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL29049202 | 0.90 | POLB (0.53) | POLBMAPTTP53GAAMAPK1 | |
| Propionic Acid SCHEMBL29049218 | 0.85 | HSD17B10 (0.54) | POLBMAPTTP53GAAMAPK1 | |
| Malonic Acid SCHEMBL29049213 | 0.84 | HSD17B10 (0.55) | POLBMAPTTP53GAAMAPK1 | |
| Bicarbonate SCHEMBL29049243 | 0.84 | HSD17B10 (0.58) | POLBMAPTTP53GAAMAPK1 | |
| Oxalic Acid SCHEMBL29049203 | 0.82 | HSD17B10 (0.56) | POLBMAPTTP53GAAMAPK1 | |
| Acetic Acid SCHEMBL29049224 | 0.82 | HSD17B10 (0.56) | POLBMAPTTP53GAAMAPK1 | |
| Chloroacetic Acid SCHEMBL29049239 | 0.81 | HSD17B10 (0.52) | POLBMAPTTP53GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL4373569 | 0.79 | HSD17B10 (0.58) | POLBMAPTTP53GAAMAPK1 | |
| Bromide SCHEMBL29049211 | 0.79 | HSD17B10 (0.58) | POLBMAPTTP53GAAMAPK1 | |
| Iodide SCHEMBL29049215 | 0.79 | HSD17B10 (0.58) | POLBMAPTTP53GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362459-A1 | Polyacrylate polymers utilizing substituted urea retarder | Zeon Chemicals USA, Inc. (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0309794-A2 | No-post-cure method of curing polyacrylate polymers | Zeon Chemicals USA, Inc. (US) | 1989-04-05 | — | — | EP | disclosed |