Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14040992 | 0.85 | SMN1; SMN2 (0.41) | HTT | |
| SCHEMBL3360383 | 0.81 | POLB (0.50) | POLBNQO2CYP19A1GSK3BMEN1 | |
| SCHEMBL14284005 | 0.79 | KDM4E (0.47) | POLBNQO2CYP19A1CYP1A2CYP2D6 | |
| SCHEMBL24986410 | 0.78 | POLB (0.44) | POLBNQO2CYP19A1CYP1A2CYP2D6 | |
| SCHEMBL4942498 | 0.77 | POLB (0.50) | POLBCYP1A2CYP2D6GSK3BMEN1 | |
| SCHEMBL10430644 | 0.77 | POLB (0.48) | POLBNQO2CYP19A1CYP1A2CYP2D6 | |
| SCHEMBL10430981 | 0.77 | POLB (0.43) | POLBNQO2CYP19A1CYP1A2CYP2D6 | |
| SCHEMBL8488782 | 0.77 | LMNA (0.51) | POLBNQO2CYP19A1CYP1A2CYP2D6 | |
| SCHEMBL12446382 | 0.75 | NQO2 (0.46) | NQO2CYP19A1 | |
| SCHEMBL8334782 | 0.75 | NQO2 (0.46) | NQO2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404694-A2 | 4-hydroxy-8-methoxy-2-methyl-6, 7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline, and process for preparing the same | MITSUBISHI KASEI CORPORATION (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0387156-A2 | A process for preparing cotarnine | MITSUBISHI KASEI CORPORATION (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4769480-A | Benzylamine derivative | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0214051-A2 | Benzylamine derivative | MITSUBISHI KASEI CORPORATION (JP) | 1987-03-11 | — | — | EP | disclosed |