SCHEMBL10430786

SCHEMBL10430786

Oc1cccc(CC(O)O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.50
GABRB2 P47870 2/20 0.50
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.48
HPGD P15428 2/20 0.48
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 2/20 0.48
ADAMTS4 O75173 1/20 0.48
EGFR P00533 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
FYN P06241 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
CA6 P23280 1/20 0.48
CDK2 P24941 1/20 0.48
MMP12 P39900 1/20 0.48
RECQL P46063 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5463179 0.83 GABRA1 (0.47) GABRA1GABRB2ALDH1A1LMNAHPGD
SCHEMBL8931392 0.81 HSPA5 (0.56) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL29812362 0.80 GABRA1 (0.59) GABRA1GABRB2ALDH1A1LMNAHPGD
SCHEMBL1053654 0.80 GABRA1 (0.79) GABRA1GABRB2ALDH1A1LMNAHPGD
SCHEMBL10962332 0.78 GABRA1 (0.38) GABRA1GABRB2ALDH1A1LMNAHPGD
SCHEMBL6535663 0.78 SMN1; SMN2 (0.49) GABRA1GABRB2ALDH1A1LMNAHPGD
SCHEMBL490685 0.77 KMT2A (0.52) GABRA1GABRB2ALDH1A1LMNAHPGD
SCHEMBL632694 0.77 GABRA1 (0.55) GABRA1GABRB2
SCHEMBL7799142 0.77 IAPP (0.46) GABRA1GABRB2ALDH1A1LMNAHPGD
SCHEMBL2788678 0.75 HSPA5 (0.62) GABRA1GABRB2ALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117298325-A Preparation method of calcium-containing polymer hemostatic sponge and sponge preparation device 中国科学院长春应用化学研究所 2023-12-29 CN disclosed
EP-0378858-A2 Process for the preparation of branched thermoplastic polycarbonates GENERAL ELECTRIC COMPANY (US) 1990-07-25 EP disclosed