SCHEMBL632694

SCHEMBL632694

CC(N)Cc1cccc(O)c1O

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.55
GABRB2 P47870 1/20 0.55
TAAR1 Q96RJ0 5/20 0.48
SLC6A2 P23975 3/20 0.48
MAOA P21397 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
CYP2A6 P11509 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5914402 0.83 SLC6A2 (0.50) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL1053654 0.83 GABRA1 (0.79) GABRA1GABRB2
SCHEMBL4742791 0.83 SLC6A2 (0.50) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL266416 0.83 SLC6A2 (0.50) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL29812362 0.83 GABRA1 (0.59) GABRA1GABRB2
SCHEMBL14478220 0.82 SOS2 (0.54) GABRA1GABRB2TAAR1SLC6A2MAOA
SCHEMBL5463179 0.82 GABRA1 (0.47) GABRA1GABRB2TAAR1
Iodide SCHEMBL6052802 0.82 SLC6A2 (0.49) TAAR1SLC6A2MAOASLC6A4SLC6A3
Hydrochloric Acid SCHEMBL724080 0.82 SLC6A2 (0.49) TAAR1SLC6A2MAOASLC6A4SLC6A3
Bromide SCHEMBL6052803 0.82 SLC6A2 (0.49) TAAR1SLC6A2MAOASLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117127434-A Preparation method for improving mechanical strength of carbon paper for proton exchange membrane fuel cell 浙江科技学院 2023-11-28 CN claimed
CN-115505439-A Surface modification method of universal micro-nano powder material 中国科学院兰州化学物理研究所 2022-12-23 CN claimed
CN-112064206-B Honeysuckle and forsythia PP spun-bonded non-woven fabric 中科纺织研究院(青岛)有限公司 2021-07-27 CN claimed
CN-112281311-A PP spunbonded non-woven fabric containing lotus leaves, isatis roots and aloes 中科纺织研究院(青岛)有限公司 2021-01-29 CN claimed
CN-112064206-A Honeysuckle and forsythia PP spun-bonded non-woven fabric 中科纺织研究院(青岛)有限公司 2020-12-11 CN claimed
EP-1480677-B1 COMPOSITION FOR STABILIZING HYALURONIC ACID IOLTECH (FR) 2012-02-29 EP claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
CN-117127434-A Preparation method for improving mechanical strength of carbon paper for proton exchange membrane fuel cell 浙江科技学院 2023-11-28 CN disclosed
CN-117127434-A Preparation method for improving mechanical strength of carbon paper for proton exchange membrane fuel cell 浙江科技学院 2023-11-28 CN disclosed
CN-115505439-A Surface modification method of universal micro-nano powder material 中国科学院兰州化学物理研究所 2022-12-23 CN disclosed
CN-112807289-B Method for modifying surface of living cell based on nano-particles and nano-particles used by method 中国医学科学院生物医学工程研究所 2022-12-06 CN disclosed
CN-113749190-A Compound feed additive for preventing and treating diarrhea of cashmere goat lambs as well as preparation method and application of compound feed additive 辽宁农业职业技术学院 2021-12-07 CN disclosed
CN-112064206-B Honeysuckle and forsythia PP spun-bonded non-woven fabric 中科纺织研究院(青岛)有限公司 2021-07-27 CN disclosed
CN-112281311-A PP spunbonded non-woven fabric containing lotus leaves, isatis roots and aloes 中科纺织研究院(青岛)有限公司 2021-01-29 CN disclosed
CN-112064206-A Honeysuckle and forsythia PP spun-bonded non-woven fabric 中科纺织研究院(青岛)有限公司 2020-12-11 CN disclosed
EP-1866357-B1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF SHOWA DENKO KK (JP) 2012-02-22 EP disclosed
US-8044235-B2 (Meth) acryloyl group-containing aromatic isocyanate compound and production process thereof SHOWA DENKO K.K. (JP) 2011-10-25 US disclosed
US-20090054543-A1 (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof SHOWA DENKO K.K. (JP) 2009-02-26 US disclosed
EP-1866357-A1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF Showa Denko K.K. (JP) 2007-12-19 EP disclosed
WO-2006103979-A1 (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF SHOWA DENKO K.K. (JP) 2006-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054543-A1 (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof PRMT5, ACR, PRMT1 GABRA1 1839/4885GABRB2 1960/4885TAAR1 1767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.