SCHEMBL10431024

SCHEMBL10431024

C/C=C\c1ccccc1Oc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.49
SRC P12931 1/20 0.46
TGFBR1 P36897 1/20 0.46
MAPT P10636 5/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
BCHE P06276 1/20 0.46
RAB9A P51151 1/20 0.46
HTT P42858 2/20 0.44
ABCB1 P08183 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
GAA P10253 2/20 0.43
AKR1C3 P42330 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPK1 P28482 2/20 0.41
KDM4E B2RXH2 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DRD2 P14416 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8712513 1.00 ELANE (0.49) ELANESRCTGFBR1MAPTNPC1
SCHEMBL16116225 0.91 HTT (0.45) ELANEMAPTNPC1LMNABCHE
SCHEMBL9504411 0.90 GAA (0.49) ELANEMAPTLMNAHTTKMT2A
SCHEMBL9504416 0.90 GAA (0.49) ELANEMAPTLMNAHTTKMT2A
SCHEMBL29679676 0.89 MAPT (0.42) ELANESRCTGFBR1MAPTNPC1
SCHEMBL16116176 0.89 MAPT (0.42) ELANESRCTGFBR1MAPTNPC1
SCHEMBL7896154 0.87 LMNA (0.47) MAPTNPC1LMNABCHERAB9A
SCHEMBL7896151 0.87 LMNA (0.47) MAPTNPC1LMNABCHERAB9A
SCHEMBL9497002 0.82 AKR1C3 (0.52) ELANEMAPTKMT2AGAAAKR1C3
SCHEMBL9496987 0.82 AKR1C3 (0.52) ELANEMAPTKMT2AGAAAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392979-A2 Curable mixtures containing a bismaleimide and a propenyl compound CIBA-GEIGY AG (CH) 1990-10-17 EP claimed
US-20210147680-A1 RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER, AND SEMICONDUCTOR DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-05-20 US disclosed
EP-3790039-A1 RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER, AND SEMICONDUCTOR DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-03-10 EP disclosed
EP-0392979-A2 Curable mixtures containing a bismaleimide and a propenyl compound CIBA-GEIGY AG (CH) 1990-10-17 EP disclosed