SCHEMBL9496987

SCHEMBL9496987

C/C=C/c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.52
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 1/20 0.44
ELANE P08246 1/20 0.42
ATM Q13315 3/20 0.42
CDC25B P30305 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TDP1 Q9NUW8 3/20 0.41
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41
CCR6 P51684 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TLR9 Q9NR96 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SRD5A2 P31213 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497002 1.00 AKR1C3 (0.52) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL27800989 0.88 LIG1 (0.56) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL6936487 0.86 MAPT (0.46) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL6447089 0.86 MAPT (0.46) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL6838795 0.85 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL29263440 0.83 AKR1C3 (0.53) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL8712513 0.82 ELANE (0.49) AKR1C3GAAMAPTKMT2AELANE
SCHEMBL10431024 0.82 ELANE (0.49) AKR1C3GAAMAPTKMT2AELANE
SCHEMBL357341 0.82 ALDH1A1 (0.52) AKR1C3MAPTALDH1A1KMT2ATDP1
SCHEMBL728576 0.82 ALDH1A1 (0.52) AKR1C3MAPTALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350069-B1 METHOD FOR OXIDIZING UNSATURATED AROMATIC COMPOUNDS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
US-4967009-A REACTING UNSATURATED AROMATIC COMPOUNDS WITH AROMATIC IODOSYL COMPOUNDS TO YIELD AROMATIC ALDEHYDES OR KETONES NIPPON PETROCHEMICALS CO., LTD. (JP) 1990-10-30 US disclosed
EP-0350069-A2 Method for oxidizing unsaturated aromatic compounds NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-01-10 EP disclosed