Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | TFEB | P19484 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896154 | 1.00 | LMNA (0.47) | LMNAMAPTNPC1RAB9ABCHE | |
| SCHEMBL10431024 | 0.87 | ELANE (0.49) | LMNAMAPTNPC1RAB9ABCHE | |
| SCHEMBL8712513 | 0.87 | ELANE (0.49) | LMNAMAPTNPC1RAB9ABCHE | |
| SCHEMBL29679676 | 0.85 | MAPT (0.42) | LMNAMAPTNPC1RAB9ABCHE | |
| SCHEMBL16116176 | 0.85 | MAPT (0.42) | LMNAMAPTNPC1RAB9ABCHE | |
| SCHEMBL9504456 | 0.84 | GAA (0.56) | LMNAMAPTNPC1RAB9ABCHE | |
| SCHEMBL9504448 | 0.84 | GAA (0.56) | LMNAMAPTNPC1RAB9ABCHE | |
| SCHEMBL12227188 | 0.80 | GAA (0.55) | LMNAHTTMEN1KMT2AGAA | |
| SCHEMBL158895 | 0.80 | GAA (0.55) | LMNAHTTMEN1KMT2AGAA | |
| SCHEMBL158896 | 0.80 | GAA (0.55) | LMNAHTTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313248-B1 | CURABLE SOLID AROMATIC DIAMINE BISMALEIMIDE AND LIQUID ALKENYLPHENYL RESINS; DECREASED WEIGHT LOSS UPON AGING | CYTEC TECHNOLOGY CORP. | 2001-11-06 | — | — | US | disclosed |