Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539164 | 0.81 | SMN1; SMN2 (0.65) | MAPTCASP3CA12CA1CA2 | |
| SCHEMBL31177679 | 0.75 | GABRA5 (0.56) | MAPTPOLBCASP3CA12CA1 | |
| SCHEMBL12992243 | 0.75 | TDP1 (0.46) | MAPTPOLBCASP3CA12CA1 | |
| SCHEMBL30204402 | 0.74 | BRPF1 (0.53) | MAPTCASP3CA12CA1CA2 | |
| SCHEMBL9497513 | 0.74 | LCK (0.48) | MAPTPOLBCASP3CA12CA1 | |
| SCHEMBL10744197 | 0.73 | KDM4E (0.41) | MAPTPOLBCASP3CA12CA1 | |
| SCHEMBL18995951 | 0.72 | KDM4E (0.51) | MAPTPOLBCASP3TDP1SMN1; SMN2 | |
| SCHEMBL553819 | 0.72 | MEN1 (0.54) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL19231292 | 0.72 | KDM4E (0.48) | MAPTPOLBCASP3CA12CA1 | |
| SCHEMBL31471535 | 0.71 | L3MBTL1 (0.50) | MAPTCASP3CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |